Vascular risk factors and Alzheimer’s disease

Vascular risk factors and Alzheimer’s disease

The various forms of dementia have traditionally been classified according to the criteria established by Kraepelin, Alzheimer and Biswanger and subsequently revised by Sir M. Roth. Vascular risk factors have always been considered to cause vascular dementia, while Alzheimer's disease was considered to be caused by other, poorly defined degenerative factors. However, in the last few years, a se...

Risk factors for vascular dementia and Alzheimer disease.

Alzheimer disease and vascular cognitive impairment are important causes of cognitive decline in the elderly. It has now been shown that vascular risk factors have measurable negative effects on the brain and are associated with cognitive impairment. We review vascular factors that might be responsible to cognitive decline in Alzheimer disease and vascular cognitive impairment and the correspon...

Vascular calcification in chronic kidney disease: types and risk factors

Magnesium and Alzheimers Disease: The Cholinergic Hypothesis

The cholinergic deficit in Alzheimer’s disease (AD) remains the cornerstone for the understanding of chemical signal transfer. Hypofunctions of cholinergic systems are significantly involved in the signs and symptoms of senile dementia of the Alzheimer type. Cognitive deficits in AD have been widely associated with dysfunction of the cholinergic system. As a diagnostic marker of AD the activity...

Reduced Risk Factors for Vascular Disorders in Parkinson Disease Patients

Background and Purpose—Sympathetic hyperactivity is a contributing cause of vascular disorders because it increases blood pressure, blood sugar, and blood lipids. Pervasive compromise of the central and peripheral autonomic nervous systems is common in idiopathic Parkinson disease (IPD) resulting in reduced sympathetic and parasympathetic function. We hypothesized that IPD was associated with r...